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Structurally Diversified Calix[3]phenoxazines: Synthesis, Solid-State Conformational Investigation, and Host–Guest Chemistry

Lijun Mao, Fengwu Li, Lingzi Huang, Xin Qu, Ke Wang, Yanjing Zhang, Da Ma

2023Organic Letters20 citationsDOI

Abstract

]phenoxazines, are reported. Structurally diversified calix[3]phenoxazines with different substitutes on nitrogen atoms and methylene bridges are synthesized with a yield of 30%-70%. Single crystal structure and density function theory calculation show calix[3]phenoxazines possess electron-rich cavities, which can selectively encapsulate suitable electron-deficient guests through multiple noncovalent interactions.

Topics & Concepts

PhenoxazineChemistryYield (engineering)Solid-stateMethyleneCombinatorial chemistryCrystallographyStereochemistryComputational chemistryOrganic chemistryPhysical chemistryMaterials scienceMetallurgyMedicinePhenothiazinePharmacologySupramolecular Chemistry and ComplexesLuminescence and Fluorescent MaterialsMolecular Sensors and Ion Detection