Thyme oil and thymol abrogate doxorubicin-induced nephrotoxicity and cardiotoxicity in Wistar rats via repression of oxidative stress and enhancement of antioxidant defense mechanisms
Osama M. Ahmed, Sanaa R. Galaly, Mai Raslan, Mennah-Allah M. A. Mostafa
Abstract
This study aimed to assess the preventive effects of thyme oil and thymol on doxorubicin (DOX)-induced renotoxicity, cardiotoxicity, and oxidative stress in Wistar rats. Thyme oil was subjected to GC-MS analysis, which indi... | Find, read and cite all the research you need on Tech Science Press
Topics & Concepts
CardiotoxicityThymolOxidative stressNephrotoxicityDoxorubicinAntioxidantPharmacologyEssential oilChemistryToxicologyTraditional medicineMedicineFood scienceToxicityBiochemistryBiologyInternal medicineChemotherapyOrganic chemistryChemotherapy-induced cardiotoxicity and mitigation