Vitamin D intakes and health outcomes in infants and preschool children: Summary of an evidence report
Andrew R. Beauchesne, Kelly Copeland Cara, Danielle M. Krobath, Laura Paige Penkert, Shruti P. Shertukde, Danielle S. Cahoon, Belen Prado, Ruogu Li, Qisi Yao, Jing Huang, Tee Reh, Mei Chung
Abstract
BACKGROUND: A systematic review was commissioned to support an international expert group charged to update the Food and Agriculture Organisation of the United Nations (FAO)/World Health Organisation (WHO)'s vitamin D intake recommendations for children aged 0-4 years. MATERIALS AND METHODS: week of June 2020 according to key questions formulated by the FAO/WHO. Relevant studies were summarised and synthesised by key questions and by health outcomes using the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach. RESULTS: on two of the upper limit outcomes - hypercalcemia and hypercalciuria. CONCLUSIONS: supplements to infants/children) on increasing serum 25(OH)D concentrations. However, currently there is no consensus on the definitions of vitamin D status, e.g. deficiency, insufficiency, sufficiency and toxicity, based on serum 25(OH)D concentrations.This systematic review provided an international expert group a foundation and core set of data through intake-response modelling to help set vitamin D nutrient reference values for infants and children up to 4 years of age.