Radiolabelling and preclinical characterization of 89Zr-Df-radiolabelled bispecific anti-PD-L1/TGF-βRII fusion protein bintrafusp alfa
Ingrid J.G. Burvenich, Yit Wooi Goh, Nancy Guo, Hui Gan, Angela Rigopoulos, Diana Cao, Zhanqi Liu, Uwe Ackermann, Christian Wichmann, Alexander Franklin McDonald, Nhi Huynh, Graeme O’Keefe, Sylvia Gong, Fiona E. Scott, Linghui Li, Wanping Geng, Anup Zutshi, Lan Yan, Andrew M. Scott
Topics & Concepts
BiodistributionAvelumabIn vivoAntibodyChemistryIsotypeIn vitroFusion proteinMedicinePharmacologyImmunotherapyMonoclonal antibodyImmune systemImmunologyRecombinant DNABiochemistryBiologyPembrolizumabGeneBiotechnologyCancer Immunotherapy and BiomarkersRadiopharmaceutical Chemistry and ApplicationsPeptidase Inhibition and Analysis