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Design, synthesis, antimicrobial evaluation, and molecular modeling of new sulfamethoxazole and trimethoprim analogs as potential DHPS/DHFR inhibitors

Lina M. A. Abdel Ghany, Noha Ryad, Mohamed S. Abdel‐Aziz, Hany M. Abd El‐Lateef, Islam Zaki, Botros Y. Beshay

2024Journal of Molecular Structure13 citationsDOI

Topics & Concepts

ChemistryDHPSAntimicrobialTrimethoprimSulfamethoxazoleCombinatorial chemistryAntibioticsBiochemistryOrganic chemistryMalariaImmunologyBiologyPlasmodium falciparumPneumocystis jirovecii pneumonia detection and treatmentSynthesis and biological activitySynthesis and Biological Evaluation
Design, synthesis, antimicrobial evaluation, and molecular modeling of new sulfamethoxazole and trimethoprim analogs as potential DHPS/DHFR inhibitors | Litcius