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Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell–Derived Cardiac Organoids and Single-Cell RNA Sequencing

Karim Sallam, Dilip Thomas, Sadhana Gaddam, Nicole Lopez, Aimee Beck, Leila Beach, Albert J. Rogers, Hao Zhang, Ian Y. Chen, Mohamed Ameen, William Hiesinger, Jeffrey J. Teuteberg, June‐Wha Rhee, Ke Wang, Nazish Sayed, Joseph C. Wu

2022Circulation27 citationsDOIOpen Access PDF

Topics & Concepts

Induced pluripotent stem cellOrganoidMedicineCellStem cellRNACardiac cellCell biologyComputational biologyCancer researchEmbryonic stem cellBiologyGeneticsInternal medicineGeneTransplantation: Methods and OutcomesMechanical Circulatory Support DevicesRenal Transplantation Outcomes and Treatments
Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell–Derived Cardiac Organoids and Single-Cell RNA Sequencing | Litcius