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A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein

Hong Zhou, Xing Chen, Tao Hu, Juan Li, Hao Song, Yanran Liu, Peihan Wang, Di Liu, Jing Yang, Edward C. Holmes, Alice C. Hughes, Yuhai Bi, Weifeng Shi

2020Current Biology130 citationsDOIOpen Access PDF

Topics & Concepts

BiologyCoronavirusSpike ProteinSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)GenomeCleavage (geology)Spike (software development)Coronavirus disease 2019 (COVID-19)Virology2019-20 coronavirus outbreakGeneticsSequence alignmentComputational biologyPeptide sequenceGeneComputer scienceInfectious disease (medical specialty)DiseaseSoftware engineeringPathologyOutbreakMedicineFracture (geology)PaleontologySARS-CoV-2 and COVID-19 ResearchBat Biology and Ecology StudiesAnimal Virus Infections Studies
A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein | Litcius