Centrosome defects cause microcephaly by activating the 53BP1‐USP28‐TP53 mitotic surveillance pathway
Thao P. Phan, Aubrey L Maryniak, Christina Boatwright, Junsu Lee, Alisa Atkins, Andréa E. Tijhuis, Diana C.J. Spierings, Hisham Bazzi, Floris Foijer, Philip W. Jordan, Travis H. Stracker, Andrew J. Holland
Topics & Concepts
CentrosomeMitosisMicrocephalyCell biologyBiologyMitotic catastrophePLK1Centrosome cycleCell cycleProgrammed cell deathCancer researchCellApoptosisGeneticsMicrotubule and mitosis dynamicsCancer-related Molecular PathwaysEpigenetics and DNA Methylation