LBA43 Spartalizumab plus dabrafenib and trametinib (Sparta-DabTram) in patients (pts) with previously untreated BRAF V600–mutant unresectable or metastatic melanoma: Results from the randomized part 3 of the phase III COMBI-i trial
Paul Nathan, Reinhard Dummer, Georgina V. Long, Paolo A. Ascierto, Hussain Tawbi, Caroline Robert, Piotr Rutkowski, О. В. Леонов, Caroline Dutriaux, Mario Mandalà, Paul Lorigan, Pier Francesco Ferrucci, Keith T. Flaherty, Jan C. Brase, S. Green, T Haas, Aisha Masood, Eduard Gasal, Antoni Ribas, Dirk Schadendorf
Topics & Concepts
MedicineDabrafenibTrametinibMelanomaMutantOncologyMetastatic melanomaPhases of clinical researchInternal medicineCancer researchChemotherapyMAPK/ERK pathwayPhosphorylationVemurafenibGeneChemistryBiochemistryCAR-T cell therapy researchMelanoma and MAPK PathwaysCancer Immunotherapy and Biomarkers