Cellular Management of Zinc in Group B Streptococcus Supports Bacterial Resistance against Metal Intoxication and Promotes Disseminated Infection
Matthew J. Sullivan, Kelvin G. K. Goh, Glen C. Ulett
Abstract
during Zn stress and also enhance virulence during systemic infection in mice. These discoveries establish new molecular mechanisms of resistance to metal intoxication in bacteria; we suggest these mechanisms operate in other bacteria as a way to sustain microbial survival under conditions of metal stress, including in host environments.
Topics & Concepts
VirulenceStreptococcus agalactiaeMicrobiologyBiologyStreptococcus anginosusBacteriaGeneStreptococcusBiochemistryGeneticsNeonatal and Maternal InfectionsStreptococcal Infections and TreatmentsPneumonia and Respiratory Infections