Soluble epoxide hydrolase inhibitor protects against blood-brain barrier dysfunction in a mouse model of type 2 diabetes via the AMPK/HO-1 pathway
Jing Wu, Yuxing Zhao, Zhen Fan, Qiunan Chen, Jinliang Chen, Yue Sun, Xu-shun Jiang, Qian Xiao
Topics & Concepts
Epoxide hydrolase 2AMPKDownregulation and upregulationIn vivoDiabetes mellitusChemistryBlood–brain barrierPharmacologyIn vitroEndocrinologyMedicineInternal medicineEnzymeBiochemistryBiologyCentral nervous systemBiotechnologyProtein kinase AGeneEicosanoids and Hypertension PharmacologyHeme Oxygenase-1 and Carbon MonoxideAlcohol Consumption and Health Effects