Design, synthesis, biological evaluation, and modeling studies of novel conformationally-restricted analogues of sorafenib as selective kinase-inhibitory antiproliferative agents against hepatocellular carcinoma cells

Rawan M. Sbenati, Seyed–Omar Zaraei, Mohammed I. El–Gamal, Hanan S. Anbar, Hamadeh Tarazi, Malaka M. Zoghbor, Najma A. Mohamood, Mahta M. Khakpour, Dana M. Zaher, Hany A. Omar, Nour N. Alach, Mahmoud K. Shehata, Randa El‐Gamal