Systemic dendrimer delivery of triptolide to tumor-associated macrophages improves anti-tumor efficacy and reduces systemic toxicity in glioblastoma
Kevin Liaw, Rishi Sharma, Anjali Sharma, Sebastián Salazar, Santiago Appiani La Rosa, Rangaramanujam M. Kannan
Topics & Concepts
TriptolideDendrimerSystemic administrationMedicineCancer researchPharmacologyChemistryIn vivoApoptosisBiologyBiotechnologyBiochemistryNatural Compounds in Disease TreatmentRNA Interference and Gene DeliveryHistone Deacetylase Inhibitors Research