TGF-β1 maintains Foxp3 expression and inhibits glycolysis in natural regulatory T cells via PP2A-mediated suppression of mTOR signaling
Xuelu Chen, Feng Li, Shengfu Li, Dan Long, Juan Shan, Youping Li
Topics & Concepts
STAT5BiologyCell biologyProtein phosphatase 2Transforming growth factor betaGlycolysisCytokineFOXP3Signal transductionCancer researchPhosphorylationImmune systemPhosphataseBiochemistryImmunologyMetabolismImmune Cell Function and InteractionT-cell and B-cell ImmunologyImmunotherapy and Immune Responses