Electrochemical Carboxylative Cyclization of Propargylamines with CO<sub>2</sub> to Functionalized 2-Oxazolidinones
Zheng-Zheng Meng, Lan Zhao, Wen‐Jun Xie, Liang‐Nian He
Abstract
The electrochemical conversion of CO 2 into value-added chemicals represents a promising strategy for sustainable synthesis. Herein, we report a novel electrochemical carboxylative cyclization of propargylamines with CO 2 to access exocyclic iodo-carboxyl-vinylene 2-oxazolidinones bearing two CO 2 moieties by using tetraethylammonium iodide (Et 4 NI) as both the electrolyte and the “iodine source”, which enables the one-pot construction of C–O, C–C, C–N, and C–I bonds. The protocol proceeds under mild conditions and accommodates a broad range of substrates, providing access to functionalized 2-oxazolidinones with high structural complexity.
Topics & Concepts
ElectrochemistryChemistryIodideCombinatorial chemistryElectrolyteBearing (navigation)Supporting electrolyteCatalysisChemical synthesisNitrileElectrochemical cellNanotechnologyPlatinumElectrodeOrganic chemistryCarbon dioxide utilization in catalysisCO2 Reduction Techniques and Catalysts