Engineering autologous tumor cell vaccine to locally mobilize antitumor immunity in tumor surgical bed
Lei Fang, Zitong Zhao, Jue Wang, Pengcheng Zhang, Yaping Ding, Yanyan Jiang, Dangge Wang, Yaping Li
Abstract
T cells to activate personalized immunotherapy. This simple and powerful approach of engineered ATVs provides an alternative strategy for personalized immunotherapy and is readily transformable to various kinds of cell-based antigens to inhibit the relapse of postoperative tumors.
Topics & Concepts
ImmunityCell mediated immunityMedicineImmunologyTumor cellsCancer researchImmune systemImmunotherapy and Immune ResponsesNanoplatforms for cancer theranosticsCancer Research and Treatments