Noninvasive Vagal Nerve Stimulation for Gastroenterology Pain Disorders
Andres Gottfried‐Blackmore, Aida Habtezion, Linda Anh B. Nguyen
Abstract
Abdominal pain continues to be a major challenge and unmet need in clinical practice. Normalization of bidirectional gut-brain signaling has generated much interest as a therapeutic approach to treat chronic abdominal pain. Vagal nerve stimulation (VNS) is emerging as a potential non-pharmacologic strategy for the treatment of abdominal pain. In this review paper, we will summarize the etiologies of chronic pain in gastrointestinal disorders and discuss the rational for VNS as a therapeutic approach to chronic abdominal pain, with particular emphasis in the gammaCore stimulator which allows for noninvasive VNS.
Topics & Concepts
MedicineAbdominal painChronic painStimulationEtiologyVagus nerve stimulationTherapeutic approachVisceral painAnesthesiaIntensive care medicineVagus nerveInternal medicinePhysical therapyNociceptionReceptorDiseaseVagus Nerve Stimulation ResearchHeart Rate Variability and Autonomic ControlPain Management and Treatment