Characterization of <i>Alpinia officinarum</i> Hance polysaccharide and its immune modulatory activity in mice
Jiahao Ni, Huricha Chen, Chenglong Zhang, Qiyuan Luo, Yao Qin, Yuhui Yang, Yun Chen
Abstract
with a number-average molecular weight of 26.0 kDa and a weight-average molecular weight of 52.8 kDa. Additionally, the innate immune statuses of the mice were improved by treatment with AOHP, while no obvious damage was identified. To conclude, the immunomodulatory activity and biological safety make AOHP a viable candidate as an ingredient for healthcare drugs.
Topics & Concepts
SephadexPolysaccharideImmune systemChemistryMonosaccharidePharmacologyInnate immune systemBiochemistryTraditional medicineBiologyImmunologyMedicineEnzymeGinger and Zingiberaceae researchDermatology and Skin DiseasesPolysaccharides and Plant Cell Walls