Cyclometalated iridium(III) complexes as mitochondria-targeted anticancer and antibacterial agents to induce both autophagy and apoptosis
Bingbing Chen, Nan-Lian Pan, Jia-Xin Liao, Min-Ying Huang, Dong-Chun Jiang, Junjie Wang, Hai-Jun Qiu, Jiaxi Chen, Lin Li, Jing Sun
Topics & Concepts
AutophagyChemistryApoptosisCytotoxicityIridiumReactive oxygen speciesMitochondrionQuinolineProgrammed cell deathCell biologyIntracellularCancer cellStereochemistryCancer researchBiochemistryCancerIn vitroBiologyOrganic chemistryGeneticsCatalysisMetal complexes synthesis and propertiesQuinazolinone synthesis and applicationsSynthesis and Biological Evaluation