Single-scan ultra-selective 1D total correlation spectroscopy
P. Király, Mathias Nilsson, Gareth A. Morris, Ralph W. Adams
Abstract
Selective 1D TOCSY is a powerful tool in the assignment of NMR spectra of organic molecules. Here an order of magnitude improvement in selectivity, allowing overlapping multiplets to be excited separately, is achieved in a single scan using the very recent GEMSTONE method. The new experiment is illustrated using an antibiotic and a mixture of diastereomers.
Topics & Concepts
Two-dimensional nuclear magnetic resonance spectroscopySpectroscopyNuclear magnetic resonance spectroscopyCorrelationSpectral lineNuclear magnetic resonanceMaterials scienceChemistryAnalytical Chemistry (journal)PhysicsOrganic chemistryMathematicsGeometryQuantum mechanicsAstronomyMolecular spectroscopy and chiralityAdvanced MRI Techniques and ApplicationsAdvanced NMR Techniques and Applications