An integrated network pharmacology and transcriptomic method to explore the mechanism of the total Rhizoma Coptidis alkaloids in improving diabetic nephropathy
Yaping Xiao, Yan Liu, Lai Zhihui, Jieyao Huang, Chunming Li, Yaru Zhang, Xiaobao Gong, Jianling Deng, Xiaoli Ye, Xuegang Li
Topics & Concepts
Mechanism (biology)PharmacologyTraditional medicineMedicineDiabetic nephropathyPharmacognosyNephropathyBerberineDiabetes mellitusBiological activityChemistryBiochemistryEndocrinologyIn vitroEpistemologyPhilosophyBerberine and alkaloids researchPlant-based Medicinal ResearchPhosphodiesterase function and regulation