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<i>Coronapp</i> : A web application to annotate and monitor SARS‐CoV‐2 mutations

Daniele Mercatelli, Luca Triboli, E. Fornasari, F. Andrew Ray, Federico M. Giorgi

2020Journal of Medical Virology101 citationsDOIOpen Access PDF

Abstract

The avalanche of genomic data generated from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences and visualizing the current worldwide status of SARS-CoV-2 mutations. The webtool allows users to highlight mutations and categorize them by frequency, country, genomic location and effect on protein sequences, and to monitor their presence in the population over time. The tool is available at http://giorgilab.unibo.it/coronannotator/ for the annotation of user-provided sequences. The full code is freely shared at https://github.com/federicogiorgi/giorgilab/tree/master/coronannotator.

Topics & Concepts

AnnotationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Computational biologyMutationPopulationBiologyGeneticsGenomeComputer scienceVirologyCoronavirus disease 2019 (COVID-19)GeneMedicineDiseaseEnvironmental healthPathologyInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingBiosensors and Analytical Detection
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