A Review on Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA) of Pancreatic Lesions
Fred Karaisz, Osama O. Elkelany, Ben Davies, Gerard Lozanski, Somashekar G. Krishna
Abstract
The morbidity associated with pancreatectomies limits surgical options for high-risk patients with pancreatic neoplasms that warrant resection. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) offers a minimally invasive and potentially definitive means to treat pancreatic neuroendocrine tumors and precancerous pancreatic cystic lesions. In addition, EUS-RFA may play a role in the treatment and palliation of non-surgical cases of pancreatic adenocarcinoma. The efficacy of RFA appears to be further enhanced by systemic immunomodulatory effects. Here, we review current studies on the developing role of EUS-RFA in these pancreatic pathologies.
Topics & Concepts
MedicineRadiofrequency ablationEndoscopic ultrasoundRadiologyAdenocarcinomaPancreatic cancerPancreasAblationPancreatic carcinomaUltrasoundCancerInternal medicinePancreatic and Hepatic Oncology ResearchNeuroendocrine Tumor Research AdvancesPancreatitis Pathology and Treatment