Gut dysbiosis and body composition in cirrhosis
Roman Maslennikov, В. Т. Ивашкин, Aliya Alieva, Elena Poluektova, Anna V. Kudryavtseva, George S. Krasnov, М. С. Жаркова, Yuri Zharikov
Abstract
BACKGROUND: , a decrease in the proportion of muscle mass and an increase in extracellular fluid) are common in cirrhosis. AIM: To study the relationship between the gut microbiota and body composition in cirrhosis. METHODS: This observational study included 46 patients with cirrhosis. Stool microbiome was assessed using 16S rRNA gene sequencing. Multifrequency bioelectrical impedance analysis was performed to assess body composition in these patients. RESULTS: = 37). CONCLUSION: Changes in the amount of body cell mass and extracellular fluid are associated with changes in the gut microbiome in cirrhosis patients.