A simultaneously GSH-depleted bimetallic Cu(<scp>ii</scp>) complex for enhanced chemodynamic cancer therapy
Shuhua Cao, Xuezhao Li, Yong Gao, Fahui Li, Kaoxue Li, Xuanxuan Cao, Yiwen Dai, Lirong Mao, Shanshan Wang, Xi–Shi Tai
Abstract
. In addition, the complex could arrest the cell cycle of the G0/G1 phase, thereby inducing apoptosis rather than necrosis.
Topics & Concepts
Bimetallic stripGlutathioneChemistryCancer therapyBiophysicsCancerBiochemistryBiologyCatalysisMedicineInternal medicineEnzymeNanoplatforms for cancer theranosticsNanocluster Synthesis and ApplicationsAdvanced Nanomaterials in Catalysis