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Identification of Staphylococcus pseudintermedius Isolates from Wound Cultures by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Improves Accuracy of Susceptibility Reporting at an Increase in Cost

Helen L. Bibby, Kristen L. Brown

2021Journal of Clinical Microbiology14 citationsDOIOpen Access PDF

Abstract

< 0.0001]). Antibiotic susceptibility testing was performed in 42 isolates; none had an oxacillin MIC of 1.0 to 2.0 μg/ml, the range in which, if the isolate was misidentified as S. aureus, a very major error in susceptibility interpretation would occur. The increase in cost of the change in identification procedure was Can$17,558 per year in our laboratory, performing microbiology testing for community and acute-care patients in a zone servicing nearly 1.7 million people. While we will only continue to learn more about this emerging pathogen if we make attempts to properly identify it in clinical cultures, the additional time and cost involved may be unacceptably high in some laboratories. .

Topics & Concepts

Staphylococcus pseudintermediusMicrobiologyStaphylococcus aureusCoagulaseStaphylococcusAntibioticsStaphylococcal infectionsMedicineBiologyMicrococcaceaeBacteriaAntibacterial agentGeneticsBacterial Identification and Susceptibility TestingAntimicrobial Resistance in StaphylococcusBacterial biofilms and quorum sensing
Identification of Staphylococcus pseudintermedius Isolates from Wound Cultures by Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Improves Accuracy of Susceptibility Reporting at an Increase in Cost | Litcius