Opioids and antidepressants: which combinations to avoid
Varan Perananthan, Nicholas A. Buckley
Abstract
Some opioids such as tramadol, pethidine, dextromethorphan and tapentadol increase serotonergic activity. Fentanyl and methadone also do this but to a lesser extent.
Topics & Concepts
MedicinePain Management and Placebo EffectTreatment of Major Depression