Current advances in the application of dynamic NMR studies of DNA/RNA intra–and inter molecular effect on ring inversion rate constants for molecular diagnosis of gum cancer
Alireza Heidari, Ricardo Gobato, Lauro Figueroa Valverde
Abstract
All oncologists are marked by fundamental biochemical changes at the molecular, cellular, and tissue level. The identification and further understanding of these changes would allow improved prevention, prognosis, diagnosis and treatments, as well as overall management and disease survival. The potential of dynamic NMR biospectroscopy in molecular diagnostics relies on its ability to determine and characterize the unique fingerprint of a sample at the biochemical level for dynamic NMR studies of DNA/RNA intra-and inter molecular effect on ring inversion rate constants for molecular diagnosis of gum cancer.
Topics & Concepts
Inversion (geology)DNANuclear magnetic resonanceMaterials scienceChemistryComputational chemistryComputational biologyBiologyPhysicsBiochemistryStructural basinPaleontologyRNA and protein synthesis mechanisms