Litcius/Paper detail

Peripherally administered cannabinoid receptor 2 (CB2R) agonists lose anti-allodynic effects in TRPV1 knockout mice, while intrathecal administration leads to anti-allodynia and reduced GFAP, CCL2 and TRPV1 expression in the dorsal spinal cord and DRG

Jenny L. Wilkerson, Lauren B. Alberti, Ganesh A. Thakur, Alexandros Makriyannis, Erin D. Milligan

2021Brain Research21 citationsDOIOpen Access PDF

Topics & Concepts

TRPV1AllodyniaCannabinoid receptorPharmacologyMedicineKnockout mouseNeuropathic painCannabinoid receptor type 2NociceptionHyperalgesiaNeuroscienceReceptorAgonistInternal medicineTransient receptor potential channelBiologyCannabis and Cannabinoid ResearchIon Channels and ReceptorsPain Mechanisms and Treatments
Peripherally administered cannabinoid receptor 2 (CB2R) agonists lose anti-allodynic effects in TRPV1 knockout mice, while intrathecal administration leads to anti-allodynia and reduced GFAP, CCL2 and TRPV1 expression in the dorsal spinal cord and DRG | Litcius