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Thoracic Imaging Findings of Multisystem Inflammatory Syndrome in Children Associated with COVID-19: What Radiologists Need to Know Now

Abbey J. Winant, Einat Blumfield, Mark C. Liszewski, Jessica Kurian, Alexandra M. Foust, Edward Y. Lee

2020Radiology Cardiothoracic Imaging42 citationsDOIOpen Access PDF

Abstract

The coronavirus disease 2019 (COVID-19) global pandemic is an ongoing public health emergency, with over 4 million confirmed cases worldwide. Due to the novel nature of this coronavirus and our evolving understanding of its pathophysiology, there is continued uncertainty surrounding diagnosis and management of COVID-19, especially in pediatric patients. In addition, a new febrile hyperinflammatory Kawasaki-like syndrome (also known as multisystem inflammatory syndrome in children, or MIS-C) has emerged in pediatric patients with temporal association to COVID-19 infection. This review article aims to provide an up-to-date review of the clinical and imaging findings of pediatric MIS-C associated with COVID-19, compared with typical acute pediatric COVID-19 infection, with an emphasis on thoracic imaging findings. Supplemental material is available for this article. © RSNA, 2020.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)PandemicSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Kawasaki disease2019-20 coronavirus outbreakIntensive care medicinePediatricsDiseasePathologyInternal medicineInfectious disease (medical specialty)ArteryOutbreakKawasaki Disease and Coronary ComplicationsUltrasound in Clinical ApplicationsCOVID-19 Clinical Research Studies