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Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA

Weiruo Zhang, Irene Li, Nathan E. Reticker-Flynn, Zinaida Good, Serena Chang, Nikolay Samusik, Saumyaa Saumyaa, Yuanyuan Li, Xin Zhou, Rachel Liang, Christina S. Kong, Quynh‐Thu Le, Andrew J. Gentles, John B. Sunwoo, Garry P. Nolan, Edgar G. Engleman, Sylvia K. Plevritis

2022Nature Methods120 citationsDOIOpen Access PDF

Topics & Concepts

In situIdentification (biology)Computational biologyProtein expressionMultiplexingExpression (computer science)Computer scienceSpatial analysisBiologyPattern recognition (psychology)Artificial intelligenceChemistryBiochemistryRemote sensingGeneGeographyProgramming languageTelecommunicationsOrganic chemistryBotanySingle-cell and spatial transcriptomicsCell Image Analysis TechniquesGene expression and cancer classification
Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA | Litcius