A photo-responsive self-healing hydrogel loaded with immunoadjuvants and MoS<sub>2</sub> nanosheets for combating post-resection breast cancer recurrence
Siyu Wang, Zhuoping Qian, Huaxin Xiao, Guangwen Yang, Ziyi Zhu, Yuanzhe Gu, Junjie Song, Xin Zhang, Xinxuan Huang, Lixing Weng, Yu Gao, Wen Yang, Lianhui Wang
Abstract
-generated tumor-associated antigens promoted dendritic cell (DC) maturation. In a mouse model, PMR hydrogel-mediated photothermal therapy combined with immune checkpoint blockade effectively inhibited the recurrence of resected tumors, providing new insights for combating post-resection breast cancer recurrence.
Topics & Concepts
Photothermal therapyBreast cancerCancerSelf-healingImmune checkpointMaterials scienceResectionImmune systemCancer researchMedicineInternal medicineSurgeryNanotechnologyImmunotherapyPathologyImmunologyAlternative medicineNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesImmune cells in cancer