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Lagos Bat Virus, an Under-Reported Rabies-Related Lyssavirus

Jessica Coertse, Marike Geldenhuys, Kévin Roux, Wanda Markotter

2021Viruses31 citationsDOIOpen Access PDF

Abstract

genus, was the first rabies-related virus described in 1956. This virus is endemic to the African continent and is rarely encountered. There are currently four lineages, although the observed genetic diversity exceeds existing lyssavirus species demarcation criteria. Several exposures to rabid bats infected with LBV have been reported; however, no known human cases have been reported to date. This review provides the history of LBV and summarizes previous knowledge as well as new detections. Genetic diversity, pathogenesis and prevention are re-evaluated and discussed.

Topics & Concepts

LyssavirusRabiesVirologyBiologyRabies virusGenetic diversityVirus classificationVirusRhabdoviridaeMedicineGeneticsPopulationEnvironmental healthGenomeGeneRabies epidemiology and controlStreptococcal Infections and TreatmentsMicrobial infections and disease research