Litcius/Paper detail

Epigenetic Therapies for Cancer

Susan E. Bates

2020New England Journal of Medicine513 citationsDOI

Abstract

Cancer-cell biology is dictated by alterations in epigenetic regulation of gene expression. Mechanisms underlying these regulators are increasingly being elucidated, and agents that alter their function are being developed as treatments.

Topics & Concepts

EpigeneticsMedicineCancerEpigenesisGene expressionRegulation of gene expressionBioinformaticsComputational biologyGeneDNA methylationGeneticsBiologyInternal medicineEpigenetics and DNA MethylationHistone Deacetylase Inhibitors ResearchProtein Degradation and Inhibitors