COX-2/sEH-Mediated Macrophage Activation Is a Target for Pulmonary Protection in Mouse Models of Chronic Obstructive Pulmonary Disease
Jia‐Xi Duan, Xinxin Guan, Wei Cheng, Dingding Deng, Ping Chen, Cong Liu, Yong Zhou, Bruce D. Hammock, Hui‐Hui Yang
Topics & Concepts
COPDMedicineEpoxide hydrolase 2MacrophageInflammationImmunologyPharmacologyAlveolar macrophagePulmonary diseaseLipopolysaccharideCancer researchChemistryInternal medicineEnzymeBiochemistryIn vitroEicosanoids and Hypertension PharmacologyInflammatory mediators and NSAID effectsHeme Oxygenase-1 and Carbon Monoxide