MicroRNA-140-5p represses chondrocyte pyroptosis and relieves cartilage injury in osteoarthritis by inhibiting cathepsin B/Nod-like receptor protein 3
Lei Zhang, Jianjun Qiu, Jixiang Shi, Shaoyang Liu, Hanlin Zou
Abstract
inhibition of the CTSB/NLRP3. This study may confer a theoretical basis for the treatment of OA cartilage injury.
Topics & Concepts
PyroptosisChondrocyteInflammasomeCathepsin BChemistryCartilageMolecular biologyCell biologyCancer researchMedicineReceptorBiologyAnatomyBiochemistryEnzymeInflammasome and immune disordersCancer-related molecular mechanisms researchOsteoarthritis Treatment and Mechanisms