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Spatial multi-omics reveals the potential involvement of SPP1+ fibroblasts in determining metabolic heterogeneity and promoting metastatic growth of colorectal cancer liver metastasis

Yuzhen Gao, Xiuping Zhang, Shenglong Xia, Qing Chen, Qingchao Tong, Shaobo Yu, Rui An, Cheng Cheng, Wenbo Zou, Leilei Liang, Xinyou Xie, Zhangfa Song, Rong Liu, Jun Zhang

2025Molecular Therapy8 citationsDOIOpen Access PDF

Topics & Concepts

Colorectal cancerMetastasisBiologyCancerCancer researchComputational biologyGeneticsCancer, Hypoxia, and MetabolismCancer Research and TreatmentsEpigenetics and DNA Methylation
Spatial multi-omics reveals the potential involvement of SPP1+ fibroblasts in determining metabolic heterogeneity and promoting metastatic growth of colorectal cancer liver metastasis | Litcius