The novel histone deacetylase inhibitor pracinostat suppresses the malignant phenotype in human glioma
Mantao Chen, Luyuan Zhang, Renya Zhan, Xiujue Zheng
Topics & Concepts
GliomaCancer researchPI3K/AKT/mTOR pathwayHistone deacetylase inhibitorMMP2ApoptosisProtein kinase BBiologyCell growthFlow cytometryViability assayHistone deacetylaseMMP9U87Cell cultureMolecular biologyHistoneCancerDownregulation and upregulationMetastasisBiochemistryGeneGeneticsHistone Deacetylase Inhibitors ResearchGlioma Diagnosis and TreatmentCytokine Signaling Pathways and Interactions