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Adeno-associated viral vector serotype 9-based gene replacement therapy for SURF1-related Leigh syndrome

Qinglan Ling, Matthew Rioux, Yuhui Hu, MinJae Lee, Steven J. Gray

2021Molecular Therapy — Methods & Clinical Development32 citationsDOIOpen Access PDF

Abstract

-related Leigh syndrome patients.

Topics & Concepts

Adeno-associated virusSerotypeGeneVector (molecular biology)Genetic enhancementLocus (genetics)VirologyViral vectorBiologyGeneticsRecombinant DNAMitochondrial Function and PathologyATP Synthase and ATPases ResearchMetabolism and Genetic Disorders
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