Visible-light-promoted radical cross-coupling of <i>para</i>-quinone methides with <i>N</i>-substituted anilines: an efficient approach to 2,2-diarylethylamines
Qiao‐Lei Wu, Jing Guo, Gong‐Bin Huang, Albert S. C. Chan, Jiang Weng, Gui Lu
Abstract
An efficient protocol to access 2,2-diarylethylamines via visible-light-promoted radical reactions of para-quinone methides (p-QMs) with N-alkyl anilines has been disclosed. These reactions feature metal-free, redox-neutral, and mild reaction conditions with wide functional group compatibility.
Topics & Concepts
ChemistryQuinoneRedoxAlkylCoupling reactionFunctional groupVisible spectrumPhotochemistryRadicalReaction conditionsCombinatorial chemistryOrganic chemistryCatalysisOptoelectronicsPhysicsPolymerSynthesis of Indole DerivativesSulfur-Based Synthesis TechniquesRadical Photochemical Reactions