Base-free regio- and stereoselective photochemical synthesis of enol ethers from 1,3-dicarbonyl compounds
Keyong Zhu, Wen-Jing Yu, Xinlong Zhou, Chaogui Xu, Guanzhen Zhao, Yun Chai, Shijun Li, Yuanqing Xu, Pan Li
Abstract
-alkylation of various 1,3-dicarbonyl compounds with diazoacetates and cyclic ethers has been developed. The protocol provides a green and practical approach to highly stereoselective enol ethers under mild and base-free conditions in good to excellent yields.
Topics & Concepts
RegioselectivityEnolStereoselectivityChemistryAlkylationBase (topology)Enol etherOrganic chemistryCatalysisMathematical analysisMathematicsCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsCatalytic Alkyne Reactions