Understanding the Oral Absorption of Irbesartan Using Biorelevant Dissolution Testing and PBPK Modeling
Navpreet Kaur, Poonam Thakur, Ganesh Shete, Rahul P. Gangwal, Abhay T. Sangamwar, Arvind K. Bansal
Topics & Concepts
IrbesartanSupersaturationDissolutionChemistrySolubilityAbsorption (acoustics)PharmacokineticsDissolution testingParticle sizeAmorphous solidPhysiologically based pharmacokinetic modellingChromatographyPharmacologyBiopharmaceutics Classification SystemMaterials scienceCrystallographyOrganic chemistryEndocrinologyPhysical chemistryMedicineBlood pressureComposite materialDrug Solubulity and Delivery SystemsCrystallization and Solubility StudiesAnalytical Chemistry and Chromatography