High-resolution structure of the vWF A1 domain in complex with caplacizumab, the first nanobody-based medicine for treating acquired TTP
Hyun Tae Lee, Ui Beom Park, Tae Jun Jeong, Nahyeon Gu, Sang Hyung Lee, Yu-Jin Kim, Yong‐Seok Heo
Topics & Concepts
ChemistryVon Willebrand factorPlateletPlatelet membrane glycoproteinEpitopeGlycoproteinAntibodyMolecular biologyBiochemistryImmunologyMedicineBiologyComplement system in diseasesPlatelet Disorders and TreatmentsBlood groups and transfusion