Antifungal resistance, combinations and pipeline: oh my!
Kayla R. Stover, Brandon Hawkins, Jacob M. Keck, Katie E. Barber, David A. Cretella
Abstract
The purpose of this review is to discuss resistance mechanisms and challenges with currently available agents, provide evidence for combination therapy, and evaluate the newly available and upcoming antifungal agents and their proposed place in the treatment of challenging fungal infections.
Topics & Concepts
AntifungalCandida infectionsIntensive care medicineAntifungal drugsMedicineAntifungal drugDrug resistanceAdverse effectCandida aurisLimitingBiologyMicrobiologyPharmacologyDermatologyEngineeringMechanical engineeringAntifungal resistance and susceptibility