Comparative Metagenomic Analysis of Biosynthetic Diversity across Sponge Microbiomes Highlights Metabolic Novelty, Conservation, and Diversification
Catarina Loureiro, Anastasia Galani, Asimenia Gavriilidou, Maryam Chaib De Mares, John van der Oost, Marnix H. Medema, Detmer Sipkema
Abstract
Marine sponges and their microbial symbiotic communities are a rich source of diverse natural products (NPs). However, little is known about the sponge NP global distribution landscape and the symbionts that produce them.
Topics & Concepts
BiologySpongeMetagenomicsMicrobiomeEcologyPhylumNicheHolobiontEvolutionary biologySymbiosisGeneGeneticsBacteriaBotanyMarine Sponges and Natural ProductsMicrobial Natural Products and BiosynthesisSynthetic Organic Chemistry Methods