Is there enough evidence to classify cycloalkyl amine substituents as structural alerts?
Amit S. Kalgutkar, James P. Driscoll
Topics & Concepts
IminiumElectrophileChemistryAmine gas treatingAldehydeTertiary amineReactive intermediateDrug discoveryCovalent bondStereochemistryCombinatorial chemistryBiochemistryOrganic chemistryCatalysisSynthesis and Biological EvaluationClick Chemistry and ApplicationsPharmacogenetics and Drug Metabolism