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Radiotherapy combined with immunotherapy successfully treated one case of anaplastic thyroid cancer: A case report

Yurou Xing, Yongsheng Wang, Xin Wu

2023Frontiers in Oncology13 citationsDOIOpen Access PDF

Abstract

Background: Anaplastic thyroid cancer (ATC) is a rare but highly fatal form of thyroid cancer. This highly malignant tumor progresses rapidly and is prone to relapse and metastasis, with a poor prognosis. Novel treatments have improved survival in recent years, but the outcome of treatment is not satisfactory. Case presentation: We report a case of multiple postoperative recurrences of papillary thyroid carcinoma that later transformed into undifferentiated carcinoma. The patient's neck mass was huge and the operation was unsuitable. Then, she achieved remarkable tumor shrinkage by tislelizumab immunotherapy combined with radiotherapy. Conclusion: This case indicates that radiotherapy combined with immunotherapy is a promising treatment for ATC. Such a combined approach warrants further study.

Topics & Concepts

MedicineRadiation therapyAnaplastic thyroid cancerImmunotherapyThyroid cancerAnaplastic carcinomaCancerMetastasisThyroid carcinomaOncologyThyroidInternal medicineSurgeryRadiologyThyroid Cancer Diagnosis and TreatmentSalivary Gland Tumors Diagnosis and TreatmentMultiple and Secondary Primary Cancers
Radiotherapy combined with immunotherapy successfully treated one case of anaplastic thyroid cancer: A case report | Litcius