Disrupted mitochondrial transcription factor A expression promotes mitochondrial dysfunction and enhances ocular surface inflammation by activating the absent in melanoma 2 inflammasome
Yaqiong Li, Lei Tian, Siyuan Li, Xiaoniao Chen, Fengyang Lei, Jiayu Bao, Qianru Wu, Ya Wen, Ying Jie
Topics & Concepts
TFAMInflammasomeAIM2Gene knockdownBiologyMitochondrial DNACell biologyMolecular biologyMitochondrionMitochondrial biogenesisInflammationChemistryImmunologyApoptosisBiochemistryGeneInflammasome and immune disordersOcular Surface and Contact LensAdvanced Glycation End Products research