Elabela ameliorates doxorubicin-induced cardiotoxicity by promoting autophagic flux through TFEB pathway
Deshu Chen, Wenjie Yu, Chongbin Zhong, Qingqing Hong, Guanlin Huang, Dongdong Que, Yuxi Wang, Yashu Yang, Bowen Rui, Zhenyu Zhuang, Miaoyuan Liang, Zhicheng Ye, Xin Yan, Jiankun Lv, Ronghua Zhang, Jing Yan, Pingzhen Yang
Topics & Concepts
CardiotoxicityAutophagyTFEBProgrammed cell deathDoxorubicinPharmacologyDownregulation and upregulationCell biologyChemistryFlux (metallurgy)In vivoApoptosisMedicineInternal medicineBiologyToxicityBiochemistryChemotherapyOrganic chemistryBiotechnologyGeneApelin-related biomedical researchChemotherapy-induced cardiotoxicity and mitigationParaoxonase enzyme and polymorphisms