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Polysaccharide from Atractylodes macrocephala Koidz. alleviates pyrotinib-induced diarrhea through regulating cAMP/LKB1/AMPK/CFTR pathway and restoring gut microbiota and metabolites

Pancen Ran, Fengxian Jiang, Liying Pan, Shu Yang, Fangyan Hu, Yahui Wang, Rui Zhao, Wei-Hao Wang, Hong Mu, Juqiong Wang, Jian Wei, Guobin Fu

2025International Journal of Biological Macromolecules7 citationsDOI

Topics & Concepts

AMPKDiarrheaChemistryGut floraPolysaccharideMicrobiologyMedicineBiologyBiochemistryInternal medicineEnzymeProtein kinase AGut microbiota and healthGinseng Biological Effects and ApplicationsPharmacological Effects of Natural Compounds
Polysaccharide from Atractylodes macrocephala Koidz. alleviates pyrotinib-induced diarrhea through regulating cAMP/LKB1/AMPK/CFTR pathway and restoring gut microbiota and metabolites | Litcius